Воленрелаксин

Prop. INN (наименование, предложенное ВОЗ)

2653949-19-8

immunoglobulin single chain VH, anti-[Homo sapiens ALB (albumin, human serum albumin, HSA)], fused via peptide linkers with relaxin 2 Homo sapiens chains B and A;
Ig single chain VH humanized [Homo sapiens IGHV3-23*01 -(IGHD) - IGHJ4*01 (CDR-Kabat [5.17.17] (31-35.50-66.99-115)] (1-126), fused via peptide linker (G₄Q)₅ (127-151) to des-Asp1-relaxin 2 chain B Homo sapiens (2-29, 152-179 in the current sequence) fused via peptide linker G3SG2SG3 (180-189) to relaxin 2 chain A Homo sapiens (1-24, 190-213 in the current sequence), monomer (22-96:161-200:173-213:199-204)- tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, non- glycosylated

C₉₄₁H₁₄₇₅N₂₈₁O₂₉₅S₁₁

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