Пивекимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

2234335-84-1

immunoglobulin G1-kappa, anti-[Homo sapiens IL3RA (interleukin 3 receptor subunit alpha, interleukin 3 receptor, alpha (low affinity), CD123)], monoclonal antibody;
gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV1-46*01 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362), S122>C (446) (345-449), CHS K2>del (450)) (122-450)], (224-214')-disulfide with kappa light chain (1'-214') [V-KAPPA Musmus/Homsap (Mus musculus IGKV14-111*01 (83.2%) -IGKJ2*03 (83.3%) S120>Q (100), L124>V (104)/Homo sapiens IGKV1-16*01 (82.1%) -IGKJ2*01 (91.7%) L124>V (104), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')- bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa

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