Паридипрубарт
ParidiprubartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2641646-59-3
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TLR4 (toll like receptor 4, toll-like receptor 4, CD284)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV4-30-4*07 (85.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v38 CH2 S108, F113 (CH1 R120 (215) (119-216), hinge 1-15 (217-231), CH2 N108>S (326), L113>F (329) (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV6-21*02 (90.5%) - IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (227-227'':230-230'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV4-30-4*07 (85.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v38 CH2 S108, F113 (CH1 R120 (215) (119-216), hinge 1-15 (217-231), CH2 N108>S (326), L113>F (329) (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV6-21*02 (90.5%) - IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (227-227'':230-230'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
Структура
Иностранные названия
- Paridiprubartum (латинское)
- Paridiprubart (английское)
- Paridiprubart (немецкое)
- Paridiprubart (французское)
- Paridiprubart (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Паридипрубарт: