Марстацимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

1985638-39-8

immunoglobulin G1-lambda, anti-[Homo sapiens TFPI (tissue factor pathway inhibitor, extrinsic pathway inhibitor, EPI, lipoprotein-associated coagulation inhibitor, LACI)], Homo sapiens monoclonal antibody;
gamma1 heavy chain (1-449) [Homo sapiens VH (IGHV3- 23*01 (100%) -(IGHD) -IGHJ3*02 (100%)) [8.8.13] (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (217) (121-218), hinge (219-233), CH2 L1.4>A (237), L1.3>A (238), G1>A (240) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS K2>del (449)) (121- 449)], (223-217')-disulfide with lambda light chain (1'- 218') [Homo sapiens V-LAMBDA (IGLV1-40*01 (100%) - IGLJ2*01 (100%)) [9.3.12] (1'-112') -Homo sapiens IGLC2*01 (113-218')]; dimer (229-229'':232-232'')- bisdisulfide

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