Иерамилимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB16419

2137049-37-5

immunoglobulin G4-kappa, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-451) [VH (Homo sapiens IGHV7-4-1*02 (85.7%) -(IGHD) -IGHJ4*01 (92.3%)) [8.8.18] (1-125) -Homo sapiens IGHG4*01 (CH1 (126-223), hinge S10>P (233) (224-235), CH2 (236-345), CH3 (346-450), CHS K2>del (451)) (126- 451)], (139-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGVK1- 33*01 (83.2%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (231-231":234-234")- bisdisulfide

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