Голместроцел

Rec. INN (наименование, зарегистрированное ВОЗ)

allogeneic mesenchymal stromal cells (MSC) derived from synovial donor tissue. The primary culture is performed in serum-free media containing lipids and cytokines (e.g. epidermal growth factor (EGF), fibroblast growth factor (FGF)), followed by expansion and high density culture in media containing additional growth factors (e.g. L-ascorbic acid 2-phosphate, transforming growth factor-β (TGF-β)) to form ex vivo a three-dimensional tissue. The final cells express mesenchymal progenitor cell markers CD13, CD44, CD73, and CD90 (>95% each) and are CD11b, CD34 and CD45 negative. The MSCs are capable of differentiating into chondrocytes and produce glycosaminoglycan

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