Фровоцимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15089

1643672-70-1

immunoglobulin G4-kappa, anti-[Homo sapiens PCSK9 (proprotein convertase subtilisin/kexin type 9, neural apoptosis-regulated convertase 1, NARC1, NARC-1, proprotein convertase 9, PC9) catalytic domain], humanized monoclonal antibody;
gamma4 heavy chain (1-451) [humanized VH (Homo sapiens IGHV3-21*01 (88.8%) -(IGHD)-IGHJ4*01 (100%)) [8.8.18] (1-125) -Homo sapiens IGHG4*01 (CH1 (126- 223), hinge S10>P (233) (224-235), CH2 F1.3>A (239), L1.2>A (240) (236-345), CH3 (346-450), CHS K2>del (451)) (126-451)], (139-219')-disulfide with kappa light chain (1'-219') [humanized V-KAPPA (Homo sapiens IGKV2-28*01 (87.00%) -IGKJ1*01 (100%)) [11.3.9] (1'- 112') -Homo sapiens IGKC*01, Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (231-231":234-234")-bisdisulfide

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