Эфтозанермин алфа

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

1820660-69-2

Gln¹-human single-chain tumor necrosis factor ligand superfamily member 10 (TNFSF10, tumor necrosis factor-related apoptosis-inducing ligand, TRAIL) receptor binding domain fragment, repeat of three identical chains (2-161, 171-330, 340- 499) fused together via glycosylated linkers (162-170 connecting chain I to chain II and 331-339 connecting chain II to chain III), fused via linker (500-511) to an Fc fragment of human immunoglobulin G1 (512-740) [Homo sapiens IGHG1*03 (CH2 (524-633 (Asn⁵⁹⁰>Ser)), CH3 (634-738),CHS (739-740))], dimer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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