Цифуртилимаб
CifurtilimabМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
1629760-27-5
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5)], monoclonal antibody;
gamma1 heavy chain (1-444) [VH (Homo sapiens IGHV3-66*01 (77.6%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (211) (115-212), hinge 1-15 (213-227), CH2 (228-337), CH3 E12 (353), M14 (355) (338-442), CHS (443-444)) (115-444)], (217-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Homo sapiens IGKV1-39*01 (78.0%) -IGKJ1*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DXB11, glycoform alfa
gamma1 heavy chain (1-444) [VH (Homo sapiens IGHV3-66*01 (77.6%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (211) (115-212), hinge 1-15 (213-227), CH2 (228-337), CH3 E12 (353), M14 (355) (338-442), CHS (443-444)) (115-444)], (217-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Homo sapiens IGKV1-39*01 (78.0%) -IGKJ1*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DXB11, glycoform alfa
Структура
Иностранные названия
- Cifurtilimabum (латинское)
- Cifurtilimab (английское)
- Cifurtilimab (немецкое)
- Cifurtilimab (французское)
- Cifurtilimab (испанское)
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