Авалглюкозидаза альфа

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB16099

N (не классифицировано FDA)

1802558-87-7

modified human acid α-glucosidase produced in Chinese hamster ovary (CHO) cells, glycoform alfa, conjugated to a synthetic branched hexasaccharide containing two terminal mannose-6- phosphate (M6P), via aminooxy linkers;
prepro-lysosomal α-glucosidase (EC=3.2.1.20) (human) (57-952)- peptide, natural [Arg¹⁴³,His¹⁶⁷,Ile⁷²⁴] variant, expressed in CHO cells, glycoform alfa, with 5~9 sialyl end groups of glycan residues being oxidized and chemically modified to 5-acetamido-3,5,7- trideoxy-7-[(E)-(2-oxo-2-{2-[4-({O-(6-O-phosphono-α-D-mannopyranosyl)-(1→2)-O-α-D-mannopyranosyl-(1→6)-O-α-D-mannopyranosyl-(1→6)-O-[O-(6-O-phosphono-α-D-mannopyranosyl)-(1→2)-O-α-D-mannopyranosyl-(1→3)]-β-D-mannopyranosyl}oxy)butanoyl]hydrazinyl}ethoxy)imino]-β-L-arabino-2-heptulo-2,6-pyranosylonic acid groups

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