Анселамимаб
AnselamimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2414866-63-8
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens immunoglobulin light chain amyloid (AL) fibrils], chimeric monoclonal antibody;
gamma1 heavy chain chimeric (1-441) [Mus musculus VH (IGHV2-3*01 (92.6%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.5] (26-33.51-57.96-100)) (1-111) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 (CH1 R120 (208) (112-209), hinge 1-15 (210-224), CH2 (225-334), CH3 E12 (350), M14 (352) (335-439), CHS (440-441)) (112-441)], (214-219')-disulfide with kappa light chain chimeric (1'-219') [Mus musculus V-KAPPA (IGKV1-110*01 (95.0%) -IGKJ1*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (220-220'':223-223'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma1 heavy chain chimeric (1-441) [Mus musculus VH (IGHV2-3*01 (92.6%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.5] (26-33.51-57.96-100)) (1-111) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 (CH1 R120 (208) (112-209), hinge 1-15 (210-224), CH2 (225-334), CH3 E12 (350), M14 (352) (335-439), CHS (440-441)) (112-441)], (214-219')-disulfide with kappa light chain chimeric (1'-219') [Mus musculus V-KAPPA (IGKV1-110*01 (95.0%) -IGKJ1*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (220-220'':223-223'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Anselamimabum (латинское)
- Anselamimab (английское)
- Anselamimab (немецкое)
- Ansélamimab (французское)
- Anselamimab (испанское)
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